Boris Johnson is set to face off against the new leader of the opposition Sir Keir Starmer.
The Prime Minister hasn’t appeared at the House of Commons since he was hospitalised with coronavirus last month.
Mr Johnson will face fresh scrutiny a day after the country’s death toll exceeded that of Italy’s for the first time, making it the highest death toll in Europe.
The Prime Minister is also expected to unveil “a road map” detailing the UK’s exit strategy from strict lockdown restrictions.
Former QC Sir Keir Starmer has already led the opposition at Prime Minister’s Questions, facing off against former solicitor and first secretary of state Dominic Raab.
What time is Prime Minister’s Questions?
Prime Minister’s Questions takes place every Wednesday at noon.
The Prime Minister is required to answer questions from MPs until 12.30pm.
Where can I watch Prime Minister’s Questions?
You can watch PMQs live in full on BBC Parliament here.
If you are unable to watch live you can catch up with previous PMQs here.
What happened at the last Prime Minister’s Questions?
Last Wednesday Sir Keir Starmer put pressure on the government to deliver a clear exit strategy to the UK.
He said: “The public need to know what will happen in the next phase. On the exit strategy, I want to be absolutely clear with the First Secretary of State [Dominic Raab]: I am not asking for lockdown to be lifted.
“What I am asking is for the Government to be open with the British people about what comes next.”
He said that members of the public and businesses would need time to prepare for the next phase of restrictions on everyday life, adding: “France, Germany, Spain, Belgium, New Zealand, Australia, Scotland and Wales have all published exit plans of one sort or another.”
Mr Raab insisted that the Government would not announce its next steps until the Scientific Advisory Group for Emergencies (Sage) said it would be safe to do so. He added: “If he thinks he knows better than Sage and the scientists, he needs to explain that.”